No Priors: Artificial Intelligence | Technology | Startups
At this moment of inflection in technology, co-hosts Elad Gil and Sarah Guo talk to the world's leading AI engineers, researchers and founders about the biggest questions: How far away is AGI? What markets are at risk for disruption? How will commerce, culture, and society change? What’s happening in state-of-the-art in research? “No Priors” is your guide to the AI revolution. Email feedback to show@no-priors.com.
Sarah Guo is a startup investor and the founder of Conviction, an investment firm purpose-built to serve intelligent software, or "Software 3.0" companies. She spent nearly a decade incubating and investing at venture firm Greylock Partners.
Elad Gil is a serial entrepreneur and a startup investor. He was co-founder of Color Health, Mixer Labs (which was acquired by Twitter). He has invested in over 40 companies now worth $1B or more each, and is also author of the High Growth Handbook.
Latest Episode
Previous Episodes
- The Best of 2025 (So Far) with Sarah Guo and Elad Gil
- Reinventing the Developer Terminal with Warp Co-Founder and CEO Zach Lloyd
- Unlocking the Road to Energy Abundance with Base Power CEO and Co-Founder Zach Dell
- Humans&: Bridging IQ and EQ in Machine Learning with Eric Zelikman
- The Impact of AI, from Business Models to Cybersecurity, with Palo Alto Networks CEO Nikesh Arora
- Reinventing K-12 Education Using AI with Alpha School Principal Joe Liemandt
- AI Agents Talking to AI Agents: Reinventing Commerce with Decagon CEO Jesse Zhang
- Jared Kushner: BrainCo, Affinity Partners, and the Geopolitics of AI
- A New Operating System for Physicians with OpenEvidence Founder Daniel Nadler
- Reshaping America’s Economy for the Superintelligence Century with Jacob Helberg
- How Agentic AI is Transforming The Startup Landscape with Andrew Ng
- Chips, Neoclouds, and the Quest for AI Dominance with SemiAnalysis Founder and CEO Dylan Patel
- The Shifting Value of Content in the AI Age with Cloudflare CEO Matthew Prince
- America’s Plan to Dominate the Full AI Stack with Sriram Krishnan
- The Power of Quality Human Data with SurgeAI Founder and CEO Edwin Chen
- Asimov: Building An Omniscient RL Oracle with ReflectionAI’s Misha Laskin
- Why Platforms Win and Point Solutions Fail with Rippling CEO Parker Conrad
- Chai-2: The AI Model Accelerating Drug Discovery with Chai Discovery Co-Founders Jack Dent and Joshua Meier
- Meet AlphaEvolve: The Autonomous Agent That Discovers Algorithms Better Than Humans With Google DeepMind’s Pushmeet Kohli and Matej Balog
- The Operating System for Self Driving Cars (and Tanks, and Trucks...) With Qasar Younis and Peter Ludwig of Applied Intuition
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