ID:IOTS - Infectious Disease Insight Of Two Specialists
Join Callum and Jame, two infectious diseases doctors, as they discuss everything you need to know to diagnose and treat infections. Aimed at doctors and clinical staff working in the UK. Episode notes are available online. Queries, comments, and suggestions can be sent to the podcast email.
Episodes
140. Where do your microbiology samples go?
Callum was recently on the Primary Care Knowledge Boost podcast (https://pckb.org/), talking about what happens to microbiology specimens sent in to the lab. He did so well we thought we'd share it with you here! Enjoy... Original podcast blurb here: ---Doctors Lisa and Sara are joined by Medical microbiology and Infectious Diseases Consultant Dr Callum Mutch to follow the journey of a urine
139. Polyenes
Process your Polyene Prescribing Paralysis by partaking in this proliferous podcast pondering on the particulars of these P-harmacological agents.* *Alyssa had no part in the making of this podcast description. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all
138. RIPL - Tick borne infections
Jame and Callum are joined by Christina Petridou. In this episode we give you an overview of ticks and the key infections they transmit..., but NOT Lyme disease.Some of the infections we DO cover include: Rickettsiosis (spotted fever group), relapsing fevers, anaplasmosis, ehrlichiosis, babesiosis, TBE & CCHF. Not Lyme. THIS IS NOT A LYME DISEASE EPISODE. Show notes (including lots of summary
137. Flucytosine
Flucytosine. A much maligned antifungal, consigned to adjuvant use in Cryptococcus... WELL THAT CHANGES... well not today because the resistance barrier is shockingly low, but at least in 20m time you'll know all you need to about 5-FC! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed epi
136a. RIPL - Biosafety & Biosecurity
Lab containment levels 1-4Safety cabinets 1-3ACDP approved list of biological agents 2-4Counterterrorism act schedule 5 pathogensCat A and Cat B transport SAPO?!Confused? We're not surprised, but things will all become clear.... Once you listen to this masterclass from Dr Claire Gordon on all things biosafety and biosecurity from a UK lab perspective. Support the showSupport us on: Patreon:
136. RIPL - VHF
What could be more Rare Imported or Pathogenic than the Viral Haemorrhagic fevers?!Callum is joined again by Drs Claire Gordon and Amy Bellfield to talk all things VHF and HCID from the clinical lab perspective.We're sure you'll all be Very Happy Fans by the end of this one... Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacof
135. Terbinafine & Griseofulvin
Terbinafine! Griseofulvin!2 weird antifungals that the dermatologists use much more than us! But we here at the ID:IOTS Podcast love all our antifungal agents equally so here's an episode on literally everything you need to know about both these agents! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes
134. The Rare and Imported Pathogens Lab (RIPL)
Now this an episode, first of a triple About all the work of a lab called RIPL And we'd like to take minute now so sit right here And learn about all the horrible pathogens you now should fear Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes hav
133. Echinocandins Part 2: Rezafungin
Part 2 of 2 on Echinocandins! Tihana Bicanic gives a masterclass on Rezafungin, its use now and in the future, and gives an update on the relevant clinical trials and studies you need to know to make you a Master Echinocandologist. Alyssa and Jame are here too, but very much in receive-only mode. Listen in and find out why! Notes for this episode are found here: https://idiots.notion.site/132-133-
132. Echinocandins Part 1: the old stuff
Alyssa and Jame are joined by Tihana Bicanic, to discuss the second great antifungal drug class, Echinocandins. Part 1 of 2! (this episode we discuss the old stuff, next episode we discuss Rezafungin in more detail). Show note for this episode found here: https://idiots.notion.site/132-133-Echinocandins-2d76a1ea09d8811f800ad3a446c6726e(Note if you have any echo on the audio for this episode, try r
131. Biocide Bashing
BIOCIDES ARE COMING FOR YOU. Find out what they are, what the benefits and harms they have, and what we can do to control their use in consumer products. This was a fascinating, wide-ranging discussion on the use of agents that can affect the human/animal microbiome and environmental microbes, and the problems with trying to regulate them (in the UK at least). Hope you enjoy it. Bios: Natalie Benn
130. Azole Antifungals
Flustered by fluconazole? An ignoramus on itraconazole and isavuconazole?Puzzled by Posa? VEXED BY VORI? Never fear: You can be amazed at the Azoles, just learn how to use 'em right! That's what this episode's all about! Alyssa and Jame UNITE in the first of our episodes on antifungal drugs! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: h
129. Penicillin allergy 3: CEPH FAST
AKA Penicillin Allergy 3: Delabel Hard With A VengeanceA departure from our semi-annual penicillin allergy episode: one on cephalosporin allergy! Jame and Callum are joined by Fionnuala Cox to discuss Cephalosporin allergy in general, and the CEPH-FAST risk assessment tool in particular. Ever wanted to know how to deal with cephalosporin allergy? Listen on! Paper here: Cox F, Vogrin S, Sullivan RP
128. Antibiotic tier list
Yo ho ho, for our listeners dearestWe present an antibiotics tier list Ranking drugs from S to DIn a manner oh so ChristmassySo sit back relax and have a drink As we discourse in cladist thinkAnd if you rank a different wayWe'll forgive you this Christmas day. Proper episodes next year. See you in 2026! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee
127. Brucella
In which Callum and Jame discuss Brucellosis, named after a Scottish feminist, a disease hard to diagnose but easy to treat, as long as the treatment works which it may not. Listen on! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes
126. Capnocytophaga
It's the best pun Cal's ever done, and I don't say that lightly, son. Here's an episode on Capnocytophagia! Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review o
125. World Antimicrobial Awareness Week: AMR and Politics
It’s World Antimicrobial Awareness Week! And did you know AMR might kill us all? The British Society of Antimicrobial Chemotherapy do, and they’ve partnered up with interested politicians to drive AMR up the political agenda. But how? Jame is joined by Dr Helen Callaby, Dr Nick Brown and Dr Danny Chambers MP to discuss the workings of the UK’s All Party Parliamentary Group on AMR, the BSAC parliam
124. Moulds that cause chronic subcutaneous infections
SporotrichosisMycetomaChromoblastomycosis...Entomophthorales.Let's face it: you don't know anything about these diseases. That's OK: neither do Callum or Alyssa. That's why we've got a guest! Dr David Chandler is a Consultant Dermatologist, BSMM member and is a member of the Global Mycetoma Working Group. Listen on for everything you need to know about chronic subcutaneous
123. Moulds: Dermatophytes
Alyssa and Callum talk all things dermatophytes and Tinea:Tinea capitis – scalp, hairTinea corporis – trunk, limbs (ringworm)Tinea manuum/pedis - palms and soles (athlete’s foot)Tinea cruris - groin (jock itch)Tinea barbae - beard area and neckTinea faciale - faceTinea unguium / onychomycosis - nailsWhat does Anthropophilic mean and how do you pronounce it? Tune in to find out.Show notes for this
122. Moulds: Rare Invasive Moulds
Alyssa and Callum are joined by Dr Neil Stone to talk all things Rare, Invasive, and Mouldy. Specifically Fusarium spp., as well as Scedosporium spp. and Lomentospora prolificans. Heard of these before? No? Well listen in to find out what they are, and why they matterShow notes for this episode here: https://idiots.notion.site/122-Moulds-Rare-invasive-moulds-af70fc26e81043669c2bf3ef17c14b6c?pvs=74
121. Moulds: Mucorales
Callum and Alyssa are joined by Dr Dora Corzo-Leon to discuss all things Mucorales and Mucormycosis. Listen in to hear about:Taxonomy (and why it is confusing)PathogenesisRisk factors Clinical syndromesDiagnosticsTreatmentShow notes for this episode here: https://idiots.notion.site/121-Moulds-Mucorales-c2343d4588ea4dd19c54de538fd7fe22?pvs=74 Support the showSupport us on: Patreon: https://www.patr
120. Clinical Decision Support Systems with Biomerieux
Jame is joined by Chloe from BioMerieux to discuss clinical decision support systems and their application in Microbiology & Infectious Disease! What are they, how do they work, and what are the potential applications in antimicrobial stewardship? Listen on for details! Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly t
119. The Moulds: Aspergillus part 2, invasive and chronic disease
Callum and Jame are joined by Iain and Darius to talk through the clinical aspects of managing Aspergillosis with a particular focus on the most severe disease. Listen in to hear about current challenges around the management of both invasive and chronic Aspergillosus.Notes for this episode here: https://idiots.notion.site/118-Moulds-Aspergillus-ce3ba58d045b47b18d9641b56559c6f5?pvs=74Support the s
118. The Moulds: Aspergillus part 1, overview
Alyssa and Callum talk through Aspergillus, the first of our Moulds series. After you hear the puns in this episode you'll be fumi(n)g at us. Tune in to hear about:EpidemiologyTaxonomyPathogenesisLab identificationOn the next episode we'll be joined by some special guest to delve into the clinical aspects of the Aspergillosis.Notes for this episode here: https://idiots.notion.site/118-Mo
117. Pasteurella
Take a break from those pesky fungi to learn about another pesky gram-negative! This week it's Pasteurella. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred
116 The yeasts: Malassezia, Rhodotorula, Trichosporon, Saccharomyces
In this episode Alyssa is joined by common host Callum to talk about some less common yeast pathogens: Malassezia spp., Rhodotorula ssp., Trichosporon spp. and Saccharomyces spp. Whilst we're calling these "less common" don't let that fool you - these fungi are everywhere! They are just less commonly causing severe disease in us humans!Show notes for this episode here: https://
115. The Yeasts: PCP/Pneumocytis jirovecii
Listen to this Pretty Comprehensive Pod on PCP. Alyssa and Callum cover:EpidemiologyTaxonomy (PCP vs PJP?)Diagnosis TreatmentNote this pod episode also includes some Positively Jolly Puns on PJPNotes for this episode here: https://idiots.notion.site/115-Yeasts-Pneumocystis-jirovecii-ac05a01902b8457688b40c07020f2c2cSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeAC
114. The Yeasts: Cryptococcus part 2, management
Alyssa and Callum continue to speak to Jeremy Day about Cryptococcus, focusing on the evidence base for management. To further encapsulate your learning, be sure to listen to part 1 last week!Show notes for this episode here: https://idiots.notion.site/113-114-Yeasts-Cryptococcus-14fd0e7ed6a2478cb5734f1e21f49029?source=copy_linkSupport the showSupport us on: Patreon: https://www.patreon.com/cw/IDI
113. The yeasts: Cryptococcus part 1, overview and diagnosis
In this episode we are uncovering the most cryptic of cocci, Cryptococcus!Alyssa and Callum are joined by Jeremy Day to learn all things neo(formans) about this important pathogenic yeast. In this episode we discuss the epidemiology, clinical presentations and diagnosis of Cryptococcus.To further encapsulate your learning, be sure to listen to part 2 next week!Show notes for this episode here: htt
112. An Exacerbating Expansion on Endocarditis - part 2
In this episode, Callum and Jame discuss the latest evidence base for endocarditis assessment & management, focusing on the ESC 2023 guidance. Echocardiography indicationsSurgeryAntimicrobial treatmentsASTAND MORE…in part 1 because this is was 2-parter.Show notes for this episode here: https://idiots.notion.site/111-112-Endocarditis-2023-Update-3594d55559314434a3b87d4c30ec41f3 Support the sho
111. An Exasperating Expansion on Endocarditis, Part 1
In this episode, Callum and Jame discuss the latest evidence base for endocarditis assessment & management, focusing on the ESC 2023 guidance. Epidemiology! Prophylaxis! How to take a blood culture! A long and complicated comparison of the Duke-ISCVID and Duke-ESC criteria that doesn’t really matter because they’re both as good as each other! AND MORE…in part 2 because this is a 2-parter sorry
110. The yeasts: Candida part 3, C. auris and Candida resistance
The conclusion of the Candida trilogy focuses on the rise of the Lord of the Candida resistance mechanisms: C. auris.Alyssa and Callum are joined by returning guest Professor Tihana Bicanic to discuss the rise of C. auris. Here we highlight some resources for managing this difficult to treat Candida including the recent UKHSA updated guidelines. We also discuss anti-fungal resistance mechanisms in
109. The yeasts: Candida part 2, Candidaemia and invasive disease
Yes we've done a Candida episode, but what about SECOND Candida episode?This week in the second part of the Candida Trilogy Alyssa and Callum are joined by Professor Tihana Bicanic to discuss all things invasive Candidiasis.Listen in to hear about treatment and diagnosis of this important condition, as well as some areas of current research and the most recent guidelines from ECMM-ISHAM. (Not
108. The yeasts: Candida part 1, overview and superficial candidiasis
In this episode there will be puns where you yeast expect them...But more seriously, what does Candida albicans actually mean? What are yeasts anyway? How does this all relate to the Romans?These questions, and more, will be answered as Alyssa and Callum continue the Fungal series with this, the first in a 3-parter on all things Candida!In this episode we cover the Taxonomy (newly confusing), Epid
107. Staphylococcus aureus bacteraemia (SAB) - interpreting and applying the literature
What exciting times! Clinical trials into the management of SAB! SNAP publication on the horizon! But how do we interpret and apply the results of these trials to our patients? This week Jame and Callum are joined by Dr Clark Russell, Clinical Lecturer in Infectious Diseases to discuss:The difficulty in interpreting current clinical trials in SAB.The emerging concept of "low risk" SAB an
106. Fungal diagnostics part 2: biomarkers, serology and molecular
Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discuss the use of biomarkers such as beta-D-Glucan and galactomannan, as well as serology and molecular techniques.Notes for this episode can be found: here.Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https:/
105. Fungal Diagnostics part 1: Microscopy, Culture & Identification techniques
Callum and Alyssa are joined by Professor Malcolm Richardson to talk about all things fungal diagnostics.In this, part 1 of 2 on diagnostics we discuss the use of microscopy, histopathology and culture in diagnosing fungal infections.Notes for this episode can be found: here.Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idio
104. IDSA Difficult To Treat Gram negatives Guidance 2024 with Breakpoints podcast
IT'S A BREAKPOINTS BREAKOUT!Jame and Callum are joined by the drugnamic duo of Julie-Ann Justo & Erin McCreary from the Breakpoints podcast to delve into the IDSA DTR Gram negative Guidance.Show notes for this episode are here.Breakpoints podcast can be found here: https://breakpoints-sidp.org/Lyrics: Tryin’ to use some drugs to kill these bugsErin and Julie are PK PD thugs Gonna make the
103. Fungal infections overview and series intro
My my! Mycology?Join Callum and special co-host Alyssa for this, the first in the all new ID:IOTS Mycology Mega-series.Here we cover:What the British Society of Medical Mycology is and what they do Why we're doing this series on fungi The Global and UK Burden of fungal disease. The spectrum of fungal disease clinically, The taxonomy of these pathogens, and the WHO Fungal Pathogen List.Notes
102. AST: When there are NO breakpoints- how to use the EUCAST guidance document
So now, Loyal Listener, you know all about Susceptible, Sensitive at higher doses, Resistant, MICs, ECOFFs/ECVs and how to use the EUCAST breakpoints table....But what about the wild-west of bug-drug combos where there are no breakpoints?Well in this episode, Jame and Callum talk through the EUCAST approach to this situation.Show notes for this episode here Support the showSupport us on: Patreon:
101. AST: When there ARE breakpoints - how to use the EUCAST clinical breakpoints table
BREAKPOINTS. We all love them. S breakpoints... R breakpoints... dash, IE, NA... Wait, dash, IA, NA, Brackets?! LISTEN ON (and read the accompanying prep notes), and soon you'll know! In this episode Jame and Callum talk through the EUCAST breakpoints table and how to interpret itShow notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyM
100. AST: Rapid Identification and Molecular AST. The BCID2 & Vitek Reveal with BioMérieux
Jame is joined by Kate from BioMérieux as they take a deep dive into the BCID2 and the Vitek Reveal, 2 new devices used for rapid identification and antimicrobial susceptibility testing of blood culture isolates.Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has b
99. AST: Automated Identification & Sensitivities - the Vitek2 with BioMérieux
This week Jame is joined by Nick and Dal from BioMérieux as they take a deep dive into the Vitek2, one of the machines available for performing Automated Antimicrobial Susceptibility Testing.Note: This episode was produced in collaboration with BioMérieux. An honorarium received from them will be donated directly to charitable causes.Message from BioMérieux: Every effort has been made to ensure th
98. Meningitis Masterclass
Jame and Callum are joined by Dr Fiona McGill, lead author of the 2016 Joint Specialist Societies Meningitis Guidelines.Listen to hear an overview of the epidemiology, presentation, diagnosis and management of both bacterial and viral meningitis in the UK. Show notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeac
97. FIS 2024 part 3: Fungi, NTM, quinolones and others
HO HO HO, MERRY FISMAS!!!On the Third & Final Pod of FISmas these ID:IOTS have for you… 6 golden topics! Listen to hear about:1. Personalised approach to invasive fungal infection2. Agricultural anti-fungals and One Health3. Candida auris4. NTM standards of care5. Narrative reporting 6. Fluoroquinolones and the MHRA warnings Jame and Callum attended the Federation of Infection Societies 2024
96. FIS 2024 part 2: Viruses
HO HO HO, MERRY FISMAS!!!On the Second Pod of FISmas these ID:IOTS have for you… an all-enveloping, capsidating update on the High Consequence Infectious Diseases, measles, RSV and other viruses that you ‘R naught’ going to want to skip! Jame and Callum attended the Federation of Infection Societies 2024 annual meeting in Liverpool; here they share their reflections on the sessions they attended
95. FIS 2024 part 1: AMR & Bacteria
HO HO HO, MERRY FISMAS!!!On the First Pod of FISmas these ID:IOTS have to you… a terrifying update on the Antibiotic Apocalypse! Jame and Callum attended the Federation of Infection Societies 2024 annual meeting in Liverpool; here they share their reflections on the sessions they attended on: Bacteria and Antimicrobial resistance.Episodes on viruses, fungi etc. coming soon!Notes for this episode
94. BSAC OPAT conference 2024
Jame regales Callum with tales of his online adventure to the BSAC OPAT conference. Listen in to hear some updates on: implementation of OVIVA; subcutaneous antibiotics; and the BSAC OPAT good practice guidelines Notes for this episode here. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed epis
93. World AMR Awareness Week special: The Scottish Antimicrobial Prescribing Group (SAPG)
WAAW! This week, to celebrate World AMR Awareness Week, Callum is Joined by Andrew, Fran, Jo and Simon from the Scottish Antimicrobial Prescribing Group. Listen in to hear all about SAPG and their important work, plus we discuss WAAW and what you can do to help tackle AMR.Show notes for this episode here, including links to the resources mentioned.Sign up to be an #antibioticguardian here. Support
92. AST: What is resistance anyway? (S/I/R)
Have you ever looked at your microbiology lab report and wondered "What does resistant mean anyway?" We're sure you have (and if you haven't you should have)! And conveniently we've recorded this podcast episode to explain how it all works! We talk through the definition of S, I & R, plus some explanation on the science behind these letters.This is the first in the new
91. The ID:IOTS Guide to Tetracyclines 2: Tigecycline, Eravacycline, Omadacycline
They're new, they're weird, and we don't use them very much (or at all), but that won't stop your favourite ID:IOTS sounding off on these novel tetracyclines! In this episode we discuss: An overview of the 3 drugs, including spectrum & penetrance; pharmacokinetics; EUCAST breakpoints; resistance mechanisms; and the recommendations for use in the IDSA DTR Gram Negative guide
90. IV to Oral Switch
In which Jame talks about the rationale for IVOS, evidence base for the pros and cons, and then finishes by giving the UK oral switch criteria an absolute rinsing. Prep notes available here. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep
89. Moraxella catarrhalis
Moraxella means more moronic puns from Jame&Callum. A short episode for some short rods. Listen to hear about this coccobacillus, how to identify it in the lab and what sort of clinical syndromes it causes.Show note for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed epis
88. Where are all the new antibiotics?
Join Jame and Callum as they discuss this paper which examines where these new antibiotics are going, and why they aren't widely available.Notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are e
87. ID:IOTS guide to Tetracyclines
Join Jame and Callum on this episode about the ultimate 4 rings of power: Tetracyclines. The swiss army knife of antibiotics. We talk through the history, uses, mechanism, PK/PD and resistance.Become a pharmacophile as you learn something about pharmacophores.Shows notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.bu
86. Legionella and pontiac fever
Jame and Callum are joined by Lee John and Ella for this episode around the arch-villain of atypical pneumonia and the bogeyman of every spa. Yes Legionella pneumophila (and friends) are addressed in depth whilst this podcast is aerosolised around the world.Show notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymea
85. Bordetella and the Cough of 100 Days
You'll be whooping with knowledge after listening to this one. Come hear all about Bordetella species. From pertussis to kennel cough you'll hear it all.Show notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have
84. BIA Spring Meeting 2024
The Spring Meeting of the British Infection Assocation is a must for UK infection trainees; In this week's episode Callum summarises for Jame (who was there, but didn't take any notes) the main learning points from the meeting.Show notes for this episode here BIA membership is FREE to UK infection trainees, reasonably priced for everyone else, and paid memberships come with online access
83. BSAC Spring Conference 2024
Jame was there but Callum wasn't! The British Society for Antimicrobial Chemotherapy have several conferences throughout the year, including a Spring meeting with their AGM. But what topics were discussed, I hear you wonder? WELL WONDER NO MORE: Jame'll take you through it! Notes for this episode here Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoff
82. Microbiome 2: Microbiotoxicity
In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, finishes educating Callum and Jame (mostly Callum) on the concept of Microbiotoxicity!This episode is part 2 of 2. Here we discuss: - What is microbiotoxicity?- Risk factors for microbiotoxicity- Which antibiotics are associated with microbiotoxicity?- Mitigating microbiotoxicityhttps://www.rese
81. Microbiome 1: Introduction
In this episode, the ID:IOTS Podcast Microbiome Correspondent Dr Anastasia "Tash" Theodosiou, returns to talk about her favourite subject! This episode is part 1 of 2. Here we discuss: - What is the microbiome- Viewing the microbiome as an organ system- The microbiome's association with disease- How we study the microbiomeStay tuned for part 2 (in 1-2 weeks depending on editing), wh
80. A Poem on POET
Join us for this special 80th episode celebrating Jame's favourite trial.https://www.nejm.org/doi/full/10.1056/NEJMoa1808312Prep notes (including the images referred to in the poem) here. Special thanks to the Wikiguidelines Endocarditis crew for their work summarising the evidence this poem was based on. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffe
79. A Précis on Penicillin Binding Proteins
Presenting: More on Penicillin-Binding-Proteins than you realistically ever need to know! What is the difference between Gram positive and negative bacteria's cell walls?What is a Penicillin Binding Protein (PBP)?Why are they called PBPs?What do PBPs do?What makes MRSA resistant to (most) beta-lactams?These any many more questions answered!Notion page here - you'll need it for this one,
78. PK: Pharmacokinetics summary
One PK table to rule them allOne table to find themOne table to bring them all And in the darkness blind them… …with awesome antibiotic PK facts you can use to bedazzle your friends and enemies alike! Prep notes here. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here
77. PK: Illuminating Elimination
The last Pharmacokinetics episode had finally been …Excreted! This episode covers the ‘drug out’ bit of pharmacokinetics, including things such as: -What is clearance? -how to calculate half life and -doesn’t everything leave through the kidneys anyway? (That is sort of true, also shut up). Check out our prep notes (including for this episode) here. Support the showSupport us on: Patreon: htt
76. PK: Dithering on distribution
It's the second Pharmacokinetics episode you never knew you wanted! Let’s talk about how antibiotics are distributed around the body once absorbed, using the examples of Amoxicillin and CallumShutUpicillin (listen to episode for clarification).What exactly is the volume of distribution? Want a handy reference for the plasma protein binding of various antimicrobials? Then this is the episode f
75. PK: Blethering about Bioavailability
It's the Pharmacokinetics episode you never knew you wanted! Callum didn't know either, but never mind that let's talk about how antibiotics are absorbed, and how we can use that to improve our use of them in clinical practice. Want ammunition for that oral switch? Got someone who's doubting oral antibiotics' effectiveness? Then this is the episode for you! Check out our p
74. Nobbling the Nonfermentors: Burkholderia mallei - Glanders
In this final episode of the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the (mostly historical) pathogen Burkholderia mallei, causative agent of Glanders. We did it. We got to the end. Nonfermentors... Nobbled. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can
73. SABATaddendum
Post-publication, Callum and Jame give a little extra information on the SABATO trial in its final form compared to it's pre-publication state. Final article here:Efficacy and safety of an early oral switch in low-risk Staphylococcus aureus bloodstream infection (SABATO): an international, open-label, parallel-group, randomised, controlled, non-inferiority trial, Kaasch, Achim J Valiente, Ado
72. IDIOTS journal club: the SABATO trial
JOURNAL CLUB, YO, IT’S A SABATO!!!Join Jame and Callum as we travel back in time to when we recorded this deep dive into the SABATO trial pre-print, now peer-reviewed and published in the Lancet ID!In the next episode we'll give a little update as to how the final article differs from the preprint (not much). We also talked about in our FIS Highlights Episode 3. We loved this trial and we hop
71.Nobbling the Nonfermentors: Burkholderia pseudomallei - Melioidosis
In this penultimate episode in the Nobbling the Nonfermentors mini-series, Jame and Callum discuss the regionally important neglected tropical disease Melioidosis, caused by Burkholderia pseudomallei.This episode was based disproportionately on the following article, and we extend our thanks to the authors for thoughfully publishing it so close to us wanting to do a podcast episode on Melioid!Meum
70. Part 2 FRCPath reflections and Desert Island Antibiotics
In this Episode, Callum reflect on his recent runaway success passing the FRCPath Part 2, passes on some tips and tricks for the exam, and then we talk about what 3 antibiotics we would take with us to a Desert Island (that has all pathogens and environments where you would find said pathogens, so not just a desert apparently). 'Prepping to Pass' episodes mentioned: 40, 42, 43 & 50.T
69. Choosing an antimicrobial
How do you think about antibiotics?This Christmas we give the best gift of all: no puns in an episode.Join Jame and Callum as they talk about a method for thinking about and explaining antibiotics.Here are the show notes for this episode: https://idiots.notion.site/69-Choosing-an-antimicrobial-4e7446a91ff6413aa14924a2ba905ffa Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIO
68. Nobbling the Nonfermentors: Burkholderia cepacia Complex
Did you think the evidence base for Stenotrophomonas was bad? Well allow us to introduce you to Burkholderia cepacia complex!BCC is pretty niche but a key pathogen in people living with cystic fibrosis. We talk through the (very) limited treatment options and evidence base for this difficult bug.Prep notes for this episode here: https://idiots.notion.site/68-Burkholderia-cepacia-complex-7bba8a7c
67. FIS highlights 3 - Fungal Diagnostics, Linezolid & Serotonin Syndrome, SABATO Trial, Rabies, PK/PD Dosing of Antibiotics
Callum and Jame wrap up their thoughts on the recent FIS conference. Support the showSupport us on: Patreon: https://www.patreon.com/cw/IDIOTS_podBuyMeACoffee: https://www.buymeacoffee.com/idiotspodPrep notes for completed episodes can be found here (Not all episodes have prep notes).If you are enjoying the podcast please leave a review on your preferred podcast app!
66. FIS highlights 2 - Neurosurgical infections, parasitology reg, anti-fungals, NITCAR
Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.htmlMentioned in episode:ESCMID brain abscess guidelines: https://www.sciencedirect.com/science/article/pii/S1198743X23003993# ORAL study protocol: https://trialsjournal.biomedcentral.com/articles/10.1186/s13063-021
65. FIS highlights 1 - SNAP trial, AMR musical, S. aureus update, IPC in LMIC
Join Jame, Callum and Pals for a discussion on some highlights from FIS 2023: https://microbiologysociety.org/event/full-events-listing/federation-of-infection-societies-fis-conference.html Mentioned in episode:UCHL HLH protocol and referral details: https://www.uclh.nhs.uk/our-services/find-service/medical-specialties-1/hlh-serviceSNAP trial: https://www.snaptrial.com.au/ SNAP trial email: snap-t
64. Let’s talk tests with Let’s Talk Micro
In this episode Jame and Callum are joined by Louis, host of the let's talk micro podcast.Listen in for a discussion on what a Biomedical Scientist is and how to become one. We explore the key details that clinicians need to add to their specimen request details; and ponder how laboratory managers can make this easier for clinicians.How to request a test:https://global.oup.com/academic/produc
63. Nobbling the Nonfermentors: Stenotrophomonas maltophilia
Ready for some startling Steno statistics? In this big 1-parter, Callum & Jame go through Stenotrophomonas maltophilia, from start to finish. Unlike Pseudomonas & Acinetobacter, Steno is much less commonly seen outside of ITU & the immunocompromised; but when it shows up you have to know what you’re doing. Luckily for you, there’s basically only 2 treatments! (In Europe: you’ll see wha
62. Nobbling the Nonfermentors: Acinetobacter Part 2: Resistance & CRAB
In Part 2 of our episodes on Acinetobacter we talk abouit resistance, and then do a deep dive into the evidence base for the management of CRAB: Carbapenem-Resistant Acinetobacter Baumanii-calcoaceticus complex. Do have a look at the prep notes for this episode if you want more information on Acinetobacter. Links to podcasts mentioned in this episodeID:IOTS Episode 41: Bugs Without BordersFebrile
