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The Lancet Neurology in conversation with

The Lancet Neurology in conversation with

The Lancet Group 72 Episodes Sep 9, 2026

This podcast delves into the latest breakthroughs in brain health and neurological disease through conversations with leading researchers, neurologists, and policy experts. Each episode simplifies complex topics for a general audience, translating advanced science into actionable insights. The editors of The Lancet Neurology interview experts working on stroke, Alzheimer's disease, epilepsy, migraine, Parkinson's disease, multiple sclerosis, sleep disorders, traumatic brain injury, and other neurological challenges.

Episodes

The future of Alzheimer’s disease: blood biomarkers, brain imaging, and screening the cognitively unimpaired
The future of Alzheimer’s disease: blood biomarkers, brain imaging, and screening the cognitively unimpaired Sep 9, 2026 1729 What will Alzheimer’s disease diagnosis look like in 5–10 years? In this episode of In Conversation With…, Laura Hart is joined by the authors behind The Lancet Neurology Series on Future Directions in Alzheimer’s Disease and Related Disorders: Clifford Jack (Mayo Clinic), Charlotte Teunissen (Amsterdam UMC), Tammie Benzinger (Washington University in St Louis), and Jonathan Graff-Radford (Mayo Cl
Marjo van der Knaap on vanishing white matter
Marjo van der Knaap on vanishing white matter Aug 12, 2026 1047 For decades, a diagnosis of vanishing white matter disease came with no real treatment — so how is an old blood-pressure pill offering hope? In this episode of In Conversation With…The Lancet Neurology, Deputy Editor Laura Hart speaks with Professor Marjo van der Knaap (Amsterdam UMC) about her clinical trial of guanabenz in children with the leukodystrophy vanishing white matter. They unpack the
Jan D Lünemann and Christian Münz on Epstein–Barr virus and multiple sclerosis
Jan D Lünemann and Christian Münz on Epstein–Barr virus and multiple sclerosis Jul 15, 2026 945 In this episode, Heather Brown, Senior Editor at The Lancet Neurology, chats with Jan Lünemann (University of British Columbia, Canada) and Christian Münz (University of Zürich, Switzerland) about their Rapid Review on Epstein-Barr virus (EBV) and multiple sclerosis (MS). EBV, a common herpesvirus, has been strongly implicated in development of MS, and recent mechanistic advances are providing n
Hal Dietz discusses the role of genetics in spinal CSF leaks
Hal Dietz discusses the role of genetics in spinal CSF leaks Jun 17, 2026 983 In this episode of In Conversation With, Morgane Boillot, Senior Editor at The Lancet Neurology, speaks with connective tissue disorders — including Marfan syndrome — and human genetics expert Hal Dietz from Johns Hopkins Medicine (Baltimore, USA) about the genetics of spontaneous spinal CSF leaks. Together, they explore the clinical presentation, diagnosis, and current treatment of spontaneous sp
Tony Schapira on GBA1 Parkinson's disease
Tony Schapira on GBA1 Parkinson's disease Jun 16, 2026 1565 In this episode of In Conversation With, Elena Becker-Barroso, Editor-in-Chief of The Lancet Neurology, speaks with movement disorders specialist Tony Schapira from UCL’s Queen Square Institute of Neurology about GBA1-associated Parkinson’s disease. Together, they explore the genetic, clinical, and biochemical links between GBA1 variants, lysosomal function, Gaucher disease, alpha-synuclein pathol
Henry Brodaty and Alice Powell on cognitive resilience and ageing
Henry Brodaty and Alice Powell on cognitive resilience and ageing Apr 17, 2026 1391 Join The Lancet Neurology’s In Conversation With… as editors Elena Becker-Barroso and Laura Hart welcome Henry Brodaty and Alice Powell from the University of New South Wales (Sydney, Australia) to discuss cognitive resilience and ageing. This episode teases apart cognitive resilience, cognitive reserve, brain maintenance, and brain reserve; explores how social determinants, life-course factors, a
Niklas Mattsson-Carlgren on the use of biomarkers in the diagnosis and stratification of Alzheimer’s disease
Niklas Mattsson-Carlgren on the use of biomarkers in the diagnosis and stratification of Alzheimer’s disease Mar 18, 2026 966 In this episode, Laura Hart and Elena Becker-Barroso speak with Niklas Mattsson-Carlgren (Lund University) about the use of blood biomarkers in the diagnosis and stratification of Alzheimer's disease. They discuss two particular plasma biomarkers—p-tau217 and eMTBR-tau243—including what they measure and how a proposed practical two-step approach that uses p-tau217 as an initial screen in a neurolo
Cristina Tassorelli on migraine prevention
Cristina Tassorelli on migraine prevention Feb 18, 2026 1441 In this episode, Senior Editor Morgane Boillot speaks with Professor Cristina Tassorelli (University of Pavia, Italy) about recent advances in migraine prevention.  Together with colleagues, Tassorelli has authored a Review in the journal examining the major developments in migraine-specific pharmacological treatments over the past decade, with a particular focus on therapies targeting the CGRP pa
Inga Zerr and Simon Mead on advances in prion diseases
Inga Zerr and Simon Mead on advances in prion diseases Jan 21, 2026 1811 Our Editor-in-Chief, Elena Becker-Barroso, speaks with Inga Zerr (DZNE, Göttingen, Germany) and Simon Mead (UCL London, UK) about the latest advances in prion diseases.  In collaboration with other experts, Zerr and Mead have authored a Series in the journal that covers the genetic factors behind these diseases, and new diagnostic and prognostic biomarkers. Click here to read the full articles: ht
Julia Greenland on azathioprine for early Parkinson’s disease
Julia Greenland on azathioprine for early Parkinson’s disease Dec 19, 2025 906 Host Morgane Boillot chats with Dr Julia Greenland about a clinical trial of azathioprine in early Parkinson's disease.  Click here to read the full article: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(25)00386-2/fulltext Medical imaging and theranostics are revolutionising how we diagnose, treat, and understand disease. To meet this moment, The Lancet group is happy to announc
Ian McKeith on dementia with dementia with Lewy bodies
Ian McKeith on dementia with dementia with Lewy bodies Nov 12, 2025 1014 In this episode, host Antonia Eisenkoeck, speaks with Ian McKeith, Emeritus Professor of Old Age Psychiatry at Newcastle University, UK. They delve into the history of dementia with Lewy bodies research, highlighting key milestones and breakthroughs. Discover insights into the current state of the field and what the future holds for understanding and treating this condition. Click here to read the
Ask Nordestgaard on long-term stroke risk in women
Ask Nordestgaard on long-term stroke risk in women Oct 15, 2025 708 In this episode, host Laura Hart chats with Ask Nordestgaard (Brigham and Women's Hospital, Boston, USA) about the long-term risk of stroke in healthy women, the role of inflammation and lipoproteins, and how early biomarker screening could transform stroke prevention strategies. Click here to read the full article. Medical imaging and theranostics are revolutionising how we diagnose, treat, and u

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