Gut Podcast
The Gut Podcast is a monthly show that explores the latest research and discussions in gastroenterology and hepatology. Hosted by Dr. Philip Smith, Digital and Education Editor of Gut, the podcast features interviews with authors of articles published in the journal. It is produced by BMJ Group and the British Society of Gastroenterology, aiming to keep listeners informed about cutting-edge developments in the field. The content is educational and not a substitute for professional medical advice.
Episodes
Defining a gut-peritoneum axis in endometriosis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Wei Wang from the Department of Gynaecology and Obstetrics, First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China and the Department of Gynaecology, Shanghai Key Laboratory of Maternal Foetal Medicine, S
Eosinophilic oesophagitis: the therapeutic potential of FOXM1 inhibition
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Amanda Muir from the Department of Gastroenterology, Hepatology, and Nutrition, The Children’s Hospital of Philadelphia, and University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA, on the paper "FOXM1 in
Long-term prognosis of lean MASLD: evidence from three population-based prospective cohorts
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Shanshan Wu from the Department of Gastroenterology, Beijing Friendship Hospital, Capital Medical University, State Key Laboratory of Digestive Health, National Clinical Research Center for Digestive Disease, Beijing, China, and Profess
Managing type 2 diabetes patients with MASLD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Xiaolong Qi from Centre of Liver Disease, Zhongda Hospital, Southeast University, Nanjing, China on the paper "Two-step clinical care pathway to predict MASLD-related advanced fibrosis and long-term outcomes in type 2 diabetes" publishe
Targeting MASLD with new nanoparticles
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Zhi-Gang She from the State Key Laboratory of New Targets Discovery and Drug Development for Major Diseases, Gannan Innovation and Translational Medicine Research Institute; School of Pharmacy; First Affiliated Hospital, Gannan Medical
Performance of the China-CLIF framework in acute-on-chronic liver failure
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jun Li from the State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejian
Predicting short-term liver transplant outcomes with graft microbial DNA signature
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Fernando Lucas-Ruiz from the Biomedical Research Institute of Murcia, Murcia, Spain on the paper "Intrahepatic donor microbiota-based metataxonomic signature detected in organ preservation solution enables prediction of short-term liver transp
Screening and eradication of H pylori for gastric cancer prevention: Taipei Global Consensus II
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Jyh-Ming Liou from Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan on the paper "Screening and eradication of Helicobacter pylori for gastric cancer prevention: Taipei Global Consensus II" published in pape
Helicobacter pylori antibiotic resistance: a global challenge in search of solutions
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Christian Schulz from the Medical Department 2, LMU Munich, Munich, Germany on the paper "Helicobacter pylori antibiotic resistance: a global challenge in search of solutions" published in paper copy in Gut in October 2025.
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Effective treatment of severe acute pancreatitis using COX-2 inhibitors
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Chengwei Tang and Associate Professor Zhiyin Huang from the Department of Gastroenterology, West China Hospital of Sichuan University, Chengdu, Sichuan, China on the paper "Parecoxib sequential with imrecoxib for occurrence and remissio
Protecting against Crohn's disease with dietary whey protein
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Tao Zuo from the Guangdong Institute of Gastroenterology, The Sixth Affiliated Hospital of Sun Yat-sen University, Sun Yat-sen University, Guangzhou, Guangdong, China, on the paper "Dietary whey protein protects against Crohn’s disease
Comparing diclofenac and indomethacin for prevention of post-ERCP pancreatitis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Yanglin Pan from the State Key Laboratory of Holistic Integrative Management of Gastrointestinal Cancers and National Clinical Research Center for Digestive Diseases, Xijing Hospital of Digestive Diseases, Fourth Military Medical Univer
Studying oat ingestion in coeliac disease with purified oat protein
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Tye-Din from the Immunology Division, Walter and Eliza Hall Institute of Medical Research, and Department of Gastroenterology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia, on the paper "Purified oat protein can trigger
Predicting sensitivity to dietary emulsifiers using an in-vitro microbiota model
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Benoit Chassaing and Dr Héloïse Rytter from Microbiome-Host Interactions, INSERM, Institut Pasteur, Université Paris Cité, Paris, France, on the paper "In vitro microbiota model recapitulates and predicts individualised sensitivity to d
Antiviral treatment of chronic Hepatitis B
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Yao-Chun (Holden) Hsu from School of Medicine and Graduate Institute of Medicine, I-Shou University, Kaohsiung, Taiwan, on the paper "Effects of tenofovir disoproxil fumarate on intrahepatic viral burden and liver immune microenvironmen
Single-cell spatial profiling of immunotypes in hepatocellular carcinoma
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Bertram Bengsch and Dr Henrike Salie from the Department of Internal Medicine II, Medical Centre, University of Freiburg, Freiburg, Germany, on the paper "Spatial single-cell profiling and neighbourhood analysis reveal the determinants
Understanding the gut-adipose-liver axis and its impact on insulin action
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jordi Mayneris-Perxachs and Dr Anna Castells-Nobau from the Girona Biomedical Research Centre (IDIBGI), Girona, Spain, on the paper "Multiomics of the intestine-liver-adipose axis in multiple studies unveils a consistent link of the gut
Linking breastfeeding and atopic dermatitis in infants
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Suhua Jiang from the Department of Paediatrics, The First People's Hospital of Foshan, Foshan, People's Republic of China and Professor Lin Zhang, Assistant Professor from Department of Anaesthesia and Intensive Care and Lead Scientist,
Improving CLDN18.2 BiTEs efficacy against pancreatic cancer
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Jihui Hao from the Department of Pancreatic Cancer, Tianjin Medical University Cancer Institute and Hospital, Tianjin, China, on the paper "CD64+ fibroblast-targeted vilanterol and a STING agonist augment CLDN18.2 BiTEs efficacy agains
Gut microbiota signatures of vulnerability to food addiction in mice and humans
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Elena Martín-García and Professor Rafael Maldonado from the Laboratory of Neuropharmacology, Pompeu Fabra University and Hospital del Mar Research Institute, Barcelona, Spain and Professor Jose Manuel Fernández-Real from the Endocrinolo
Gastric intestinal metaplasia: reviewing current guidelines
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Mario Dinis-Ribeiro from the Department of Gastroenterology at Porto Comprehensive Cancer Center & RISE—Health Research Network, Porto, Portugal, on the paper "The road to a world-unified approach to the management of patients with
Exploring stem cell therapy for Hirschsprung disease
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Conor McCann from the Department of Stem Cells and Regenerative Medicine, UCL Great Ormond Street Institute of Child Health, London, UK and Dr Anestis Tsakiridis from the School of Biosciences, The University of Sheffield, Sheffield, UK on the
Protective function of sclerosing cholangitis on IBD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Samuel Huber, from the Department of Medicine, University Medical Center, Hamburg-Eppendorf, Hamburg, Germany, on the paper "Protective function of sclerosing cholangitis on IBD" published in paper copy in Gut in August 2024.
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Linking high-fat diet and liver tumorigenesis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Jianping Guo from Institute of Precision Medicine, the First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China, on the paper "High-fat diet promotes liver tumorigenesis via palmitoylation and activation of AKT" pu
Hepatocellular carcinoma in patients with liver cirrhosis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Hashem El-Serag from the Department of Gastroenterology and Hepatology, Baylor College of Medicine, Houston, Texas, USA, on the paper "Serum biomarker signature is predictive of the risk of hepatocellular cancer in patients with cirrhos
Microbiome interventions for COPD protection
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Kurtis Budden, from the Immune Health Program, The University of Newcastle and Hunter Medical Research Institute, Newcastle, NSW, Australia and Professor Philip Hansbro who is also a conjoint there and the Director of the Centenary Institute a
MASLD: a systemic metabolic disorder with cardiovascular and malignant complications
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Herbert Tilg who is the Head of Department of Internal Medicine I, Gastroenterology, Hepatology, Endocrinology & Metabolism, Medical University of Innsbruck, Innsbruck, Austria on on the Recent Advances in Clinical Practice paper "M
RE.GA.IN: the Real-world Gastritis Initiative
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Massimo Rugge who is a Honorary Professor of Pathology at the Padova University and Adjunct Professor of Medicine and Gastroenterology at the Baylor College of Medicine in Houston; Professor Peter Malfertheiner who is senior Professor o
Prebiotic diet changes neural correlates of food decision-making in overweight adults
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Veronica Witte from the Department of Cognitive Neurology, University of Leipzig Medical Center, Leipzig, Germany, on the paper "Prebiotic diet changes neural correlates of food decision-making in overweight adults: a randomised controlled wit
Lethal sepsis prevention with novel tripeptide RKH derived from Akkermansia muciniphila
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Peng Chen, from the Department of Pathophysiology, Southern Medical University, Guangzhou, China, on the paper "Novel tripeptide RKH derived from Akkermansia muciniphila protects against lethal sepsis" published in paper copy in Gut in
Special Gut Podcast: Digestive health and climate change
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews a fantastic panel of guests from around the globe including:
Professor Bishr Omary from Rutgers University, Piscataway, New Jersey, USA who was the past president of the American Gastroenterological Association
Professor Desmond Leddin from Dalho
Gastrointestinal origins for Parkinson’s disease
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Jay Pasricha, Chair of the Department of Medicine, Mayo Clinic Arizona, Arizona, USA and Bo Konings, final year medical student and researcher at the Translational Research Centre for Gastrointestinal Disorders (TARGID), KU Leuven University H
Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Julia Mayerle and Dr Simon Sirtl from the Department of Medicine II, LMU University Hospital, Munich, Germany, on the paper "Consensus definition of sludge and microlithiasis as a possible cause of pancreatitis" published in paper copy
Rome consensus on gut microbiota and faecal microbiota transplantation in IBD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Loris Lopetuso, Department of Medicine and Ageing Sciences, University of Chieti-Pescara, Italy, on the paper "The first international Rome consensus conference on gut microbiota and faecal microbiota transplantation in inflammatory bowel disease
The therapeutic potential of fasting
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Thomas Marjot, Hepatology SpR from the Oxford Liver Unit in Oxford University Hospitals and also a Wellcome Trust Clinical Research Training Fellow at the University of Oxford based at the Oxford Centre for Diabetes, Endocrinology and Metaboli
Helicobacter pylori promotes colorectal carcinogenesis
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Markus Gerhard from the Institute for Medical Microbiology, Immunology and Hygiene, School of Medicine, Technical University of Munich, Germany, on the paper "Helicobacter pylori promotes colorectal carcinogenesis by deregulating intest
Single-cell transcriptomics sheds new light on pancreas biology and disease
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Kathy DelGiorno, from the Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA, on the paper 'It is better to light a candle than to curse the darkness: single-cell transcriptomics sheds new lig
Counteracting the harm of dietary emulsifiers with Akkermansia muciniphila
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Benoit Chassaing, group leader from the “Mucosal microbiota in chronic inflammatory diseases” Team at INSERM and the Université Paris Cité, Paris, France, on the paper 'Akkermansia muciniphila counteracts the deleterious effects of diet
Antibiotic use as a risk factor for IBD
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Tine Jess, from the Center for Molecular Prediction of Inflammatory Bowel Disease, Department of Clinical Medicine, and Department of Gastroenterology and Hepatology, Aalborg University, Aalborg, Denmark, and Dr Adam S Faye, from the De
Predicting disease progression in bridging fibrosis and cirrhosis with liver stiffness
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Rohit Loomba, Professor of Medicine in the Division of Gastroenterology, and Adjunct Professor in the Division of Epidemiology at the University of California San Diego, La Jolla, California, USA on the paper 'Liver stiffness thresholds
Assessing the impact of dietary fibre on bile acid transformation by gut bacteria in mice
Dr Philip Smith, Digital and Education Editor of Gut and Honorary Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Fredrik Bäckhed, The Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden on the paper '6α-hydroxylated bile acids mediate TGR5 signalling to improve glucose metabolism upon
Autoimmune gastritis: cancer risk in consistently tested H. pylori-negative patients
Dr Philip Smith, Digital and Education Editor of Gut, and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Massimo Rugge, Pathologist at Padova University, Italy, and Adjunct Professor of Medicine at the Baylor College of Medicine in Houston, Texas, USA; and Ms Ludovica Bricca, a student at Padova University, and the youngest researcher involved in
FMT-AID trial shows effectiveness in inducing remission of ulcerative colitis
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Vineet Ahuja who is from the Department of Gastroenterology and Human Nutrition, All India Institute of Medical Sciences, New Delhi, India, on the paper 'Faecal microbiota transplantation with anti-inflammatory diet (FMT-AID) followed by anti-in
Endoscopic pyloromyotomy for the treatment of severe and refractory gastroparesis
Endoscopic pyloromyotomy (G-POEM) is a minimally invasive treatment option with promising uncontrolled outcome results in patients with gastroparesis.
Dr Philip Smith, Digital and Education Editor of Gut, interviews Professor Jan Martinek, from the Department of Hepatogastroenterology, Institute of Clinical and Experimental Medicine, Prague, Czech Republic, about his paper on this topic. The artic
Climate change: a survey of global gastroenterology society leadership
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Desmond Leddin, who is from the Department of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada, on the paper 'Climate change: a survey of global gastroenterology society leadership' published in paper copy in Gut in October 2022 and
Management of Helicobacter pylori infection — the Maastricht VI/Florence Consensus Report
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Peter Malfertheiner, Gastroenterologist, who is senior Professor of Medicine at the Ludwig Maximilian University of Munich, Munich, Germany, on the paper 'Management of Helicobacter pylori infection—the Maastricht VI/Florence Consensus Report' p
Kyoto international consensus report on the gastro-oesophageal junction
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Professor Sugano, Department of Medicine, Jichi Medical University, Tochigi, Japan, about the paper 'Kyoto international consensus report on anatomy, pathophysiology and clinical significance of the gastro-oesophageal junction'. The article is published i
A faecal microbiota signature with high specificity for pancreatic cancer
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Professor Peer Bork, Director of the Heidelberg site of the European Molecular Biology Laboratory Heidelberg, Baden, Germany on the paper 'A faecal microbiota signature with high specificity for pancreatic cancer' published in paper copy in Gut in July 2
PICaSSO Histologic Remission Index in ulcerative colitis: a novel simplified histological score
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Dr Marietta Iacucci, Associate Professor in Gastroenterology, Institute of Immunology and Immunotherapy, University of Birmingham and Consultant Gastroenterologist, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom, on the
Next-generation sequencing of bile cell-free DNA for early detection of malignant biliary strictures
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK, interviews Dr Maria Arechederra, young researcher at the Hepatology Program in the Center for Applied Medical Research (CIMA) from the University of Navarra in Pamplona, Spain, on the paper "Next-generation sequencing of bile cell-free DNA for the early detection o
Endoscopic full-thickness plication for the treatment of PPI-dependent GERD
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, Liverpool, UK interviews Dr Rakesh Kalapala, Senior Consultant Gastroenterologist & Therapeutic Endoscopist, Head of GI Motility Lab, Director of Endoscopy at the Center for Obesity & Metabolic Therapy, Member of the International Bariatric and Metabolic Endoscopy Committ
Dysosmobacter welbionis, a new human commensal bacterium preventing diet-induced obesity
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Patrice Cani, Louvain Drug Research Institute, WELBIO, Metabolism and Nutrition, UCLouvain, Brussels, Belgium and Emilie Moens de Hase a PhD student in the same institution.
This Gut podcast is focused on the paper "Dysosmobacter welbionis is a newly isolated
Gut microbiota modulates COPD pathogenesis: role of anti-inflammatory Pg-LPS
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Dr Lu from the Department of Respiratory Care, College of Medicine, Fu Jen Catholic University, Taiwan, and Drs Lai and Dr Lin from the Department of Medical Biotechnology and Laboratory Science, and Microbiota Research Center, College of Medicine, Chang Gung Universit
Proton pump inhibitors and risk of colorectal cancer
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Dr Laurent Azoulay and Dr Devin Abrahami, from the Centre for Clinical Epidemiology, Lady Davis Institute for Medical Research, and McGill University, Montreal, Canada. Dr. Abrahami is now a postdoctoral fellow at the Brigham and Women’s Hospital and Harvard Medical Sc
Sugar-sweetened beverage intake and risk of early-onset colorectal cancer among women
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Professor Cao, Associate Professor of Surgery, Division of Public Health Sciences, Department of Surgery, Washington University School of Medicine, St. Louis, Missouri. This Gut podcast is focused on the paper "Sugar-sweetened beverage intake in adulthood and adolescen
Diet quality and risk and severity of COVID-19: a prospective cohort study
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Professor Andrew Chan, Harvard Medical School, Boston, USA. This podcast is focused on the paper "Diet quality and risk and severity of COVID-19: a prospective cohort study", published in paper copy in Gut in November 2021. Link to the paper: https://gut.bmj.com/conten
Helicobacter pylori resistance to antibiotics in Europe
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Professor Megraud, University of Bordeaux, France. The podcast is focused on the paper "Helicobacter pylori resistance to antibiotics in Europe in 2018 and its relationship to antibiotic consumption in the community”, which is published in paper copy in Gut in October
Blue poo: impact of gut transit time on the gut microbiome using a novel marker
In this podcast, we'll explore how eating a ‘blue’ muffin is an inexpensive and scalable technique allowing the measurement of transit time. The method was used to assess the relationship between gut transit time and the human gut microbiome, in a study published in paper copy in Gut, in September 2021.
"Blue poo: impact of gut transit time on the gut microbiome using a novel marker" is accessible
Long-term dietary patterns associated with inflammatory features of the gut microbiome
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Laura Bolte dietitian and PhD student from the Department of Gastroenterology and Hepatology and the Department of Genetics, University of Groningen and University Medical Centre Groningen, Groningen, The Netherlands and Professor Rinse Weersma from the Department of Ga
Association between Brachyspira and irritable bowel syndrome with diarrhoea
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Gunnar C. Hansson from the Mucin Biology Groups, Department of Medical Biochemistry and Cell Biology, University of Gothenburg, Sweden. The Gut podcast is focussed on the paper "Association between Brachyspira and irritable bowel syndrome with diarrhoea" which
Effect of IBD medications on COVID-19 outcomes
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Dr Ryan Ungaro, who is an Assistant Professor at Division of Gastroenterology, Icahn School of Medicine at Mount Sinai, New York, USA. The podcast is focussed on ‘Effect of IBD medications on COVID-19 outcomes: results from an international registry’ published in paper
CLARITY IBD: Anti-SARS-CoV-2 antibody and vaccination responses in patients treated with infliximab
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Dr Tariq Ahmad and Dr Nick Kennedy, both from the Department of Gastroenterology, Royal Devon and Exeter NHS Foundation Trust, UK.
This special Gut podcast is focused on ‘Anti-SARS-CoV-2 antibody responses are attenuated in patients with IBD treated with infliximab’ w
Long-term instability of the intestinal microbiome and its associations
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Dr Fabian Frost who is a clinical scientist, internal medicine specialist and gastroenterologist in training working at the Department of Medicine A, University Medicine Greifswald, Germany.
The podcast is focussed on ‘Long-term instability of the intestinal microbiom
Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Nathanson, the Gladys Phillips Crofoot Professor of Medicine and Cell Biology at Yale University and the Director of the Yale Liver Center, Yale University School of Medicine, New Haven, Connecticut, USA. The podcast is focussed on "Neutrophils interact w
Screening and eradication of Helicobacter pylori for gastric cancer prevention
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Jyh-Ming Liou, Professor of Gastroenterology, Division of Gastroenterology and Hepatology, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan. The podcast is focussed on "Screening and eradication of Helicobacter pylori f
European Registry on Helicobacter pylori management (Hp-EuReg)
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Gisbert from the Gastroenterology Department, University Hospital of La Princesa, Madrid, Spain. The podcast is focused on "European Registry on Helicobacter pylori management (Hp-EuReg): patterns and trends in first-line empirical eradication prescriptio
Driving the efficacy of prebiotic intervention in obese patients
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, UK, interviews Professor Delzenne, President of the Louvain Drug Research Institute, at the UCLouvain, Brussels, Belgium. The podcast is focused on "Discovery of the gut microbial signature driving the efficacy of prebiotic intervention in obese patients" published in paper copy
Adipose tissue derived bacteria are associated with inflammation in obesity and type 2 diabetes
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Dr Rima Chakaroun who is a Clinician Scientist, Resident physician at the University Hospital in Leipzig, Germany, specialising in Endocrinology and Metabolic disease and a postdoctoral researcher and clinical investigator working on microbiome signatures in obesity in
Global burden of oesophageal and gastric cancer by histology and subsite in 2018
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Dr Melina Arnold from the Section of Cancer Surveillance, International Agency for Research on Cancer, Lyon, France. The podcast is focussed on "Global burden of oesophageal and gastric cancer by histology and subsite in 2018" published in paper copy in Gut in September
Intrahepatic bacterial metataxonomic signature in non-alcoholic fatty liver disease
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Silvia Sookoian, who is Head of the Department of Clinical & Molecular Hepatology and Vice-Chair of Institute of Medical Research, at the Institute of Medical Research, Strategic Alliance between the National Scientific and Technical Research Council (CONI
Efficacy of FMT for patients with IBS in a randomised, double-blind, placebo-controlled study
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Madgy El-Salhy, who is a Professor of Gastroenterology at Bergen University and Consultant Gastroenterologist at Stord Hospital, Norway, on the paper ‘Efficacy of faecal microbiota transplantation for patients with irritable bowel syndrome in a randomised, dou
Infants born to mothers with IBD present with altered gut microbiome
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Inga Peter, who is a Professor in the Department of Genetics and Genomic Sciences, Mount Sinai School of Medicine, New York, on "Infants born to mothers with IBD present with altered gut microbiome that transfers abnormalities of the adaptive immune system to
Mediterranean diet intervention alters the gut microbiome in older people
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Paul O'Toole; who is Professor of Microbial Genomics, Head of School of Microbiology and Principal Investigator in APC Microbiome Ireland, an SFI funded centre at University College Cork, Ireland, on "Mediterranean diet intervention alters the gut microbiome i
Endoscopic duodenal mucosal resurfacing for the treatment of type 2 diabetes mellitus
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Professor Jacques Bergman who is Professor of Gastrointestinal Endoscopy at the Amsterdam University Medical Center, Amsterdam on "Endoscopic duodenal mucosal resurfacing for the treatment of type 2 diabetes mellitus: one year results from the first international, open-
British Society of Gastroenterology guidance for management of IBD during the Covid-19 pandemic
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital, interviews Dr Cathryn Edwards, BSG President and Consultant Gastroenterologist at Torbay Hospital, Devon and Dr Nick Kennedy, Consultant Gastroenterologist, Royal Devon and Exeter NHS Foundation Trust on the British Society of Gastroenterology response to the coronavirus pandemic
Global patterns and trends in colorectal cancer incidence in young adults
Dr Philip Smith, Digital and Education Editor of Gut and Consultant Gastroenterologist at the Royal Liverpool Hospital interviews Ms Rebecca Siegel, Scientific Director of Surveillance Research at the American Cancer Society. Ms Rebecca Siegel is first author on the paper 'Global patterns and trends in colorectal cancer incidence in young adults' published in Gut in December 2019.
Read the article
Guidelines on the management of inflammatory bowel disease in adults
Dr Christopher Lamb, Clinical Intermediate Fellow at Newcastle University and Honorary Consultant in Gastroenterology at the Newcastle upon Tyne Hospitals NHS Foundation Trust discusses the BSG guidelines on the management of inflammatory bowel disease in adults with Associate Editor of GUT Dr Philip Smith.
Read the article: https://gut.bmj.com/content/68/Suppl_3/s1
European evidence-based guidelines on pancreatic cystic neoplasms
Evidence-based guidelines on the management of pancreatic cystic neoplasms (PCN) are lacking. The guideline discussed in this podcast is a joint initiative of the European Study Group on Cystic Tumours of the Pancreas, United European Gastroenterology, European Pancreatic Club, European-African Hepato-Pancreato-Biliary Association, European Digestive Surgery, and the European Society of Gastrointe
Viral transfer during FMT linked to better outcomes in recurrent C. diff bacterial infections
Clostridium difficile (C. difficile, C. diff or CDI) is a bacterium associated with the intake of antibiotics which causes diarrhoea. It is easily spread to others, both in hospital and a household environments.
C. Diff infections are generally treated with antibiotics. Recurrent infection is successfully treated with faecal microbiota transplantation (FMT), however the underlying mechanism of act
Colorectal cancer: research prioritisation needed in third most lethal malignancy worldwide
Prioritising research and funding could have a significant impact on reducing colorectal cancer disease burden over the next 5 years. The conclusions are included in a study recently published by Gut titled “Critical research gaps and recommendations to inform research prioritisation for more effective prevention and improved outcomes in colorectal cancer” and expanded in this podcast.
In convers
